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This page leads to our company's patented tools for
estimating the time course of blood glucose.
disruptive technology that will have a huge impact world-wide. To this day
its the only scientific approach to attaching the time dimension to
metabolic processes it provides the only scientific, non-anecdotal, base
for validating nutritional approaches such as Atkins, South Beach, or Dr.
technology gains traction, the
(GI), is still the only metric extant in the vast space between the eat
mostly carbs and the eat no carbs camps. Companies such as NutriSystems
have jumped on the glycemic index bandwagon. The South Beach diet lists
glycemic indices for several foods, and it might be of interest to quote
what a customer from Australia wrote to us: Several cereal companies,
Lowen and Sanitarium are now adding the GI code to their products, this is
purely voluntary and is being done in association with Diabetes Australia,
some packages have a description panel about the GI is all about. Again
rigid government rules apply as the use of the GI information panel. This
example illustrates the need for our solution, and not as an endorsement
itself, which, in our opinion, is a flawed, awkward metric that the
scientific world will have to replace. (The reader is invited to follow
the link, which leads to the relevant FAO/WHO publication.)
The Meal/Glucose Effect and the Insulin Effect Calculators:
The life of the insulin dependent diabetes patient is one of trying to match the effect of the injected insulin with
the glucose arriving in his or her bloodstream, primarily after a meal. These calculators will give you an
estimate of the effect any combination of foods you eat
at one sitting will have on your blood glucose level over
time, and will also give you an idea about the time effect of
any insulin shot..
(These tools are provided for educational purposes only and should not be used for arriving at any clinically related conclusions.)
The example picture to the right
shows how a combination of nutrients in food may transform to
blood glucose over time. The early spike is due to the pure sugar
content of the meal. Please note that the glucose time scale
and the insulin effect time scale are not the same. Click on
the picture to select, on the page that will open next, any specific
combination of foods you want to know about.
Go here here to see how you might use the Meal Effect Calculator
in conjunction with our software, BalancePC or LightenUp!
Unlike the natural insulin secretion from
the pancreas, which can "keep up" with the arriving glucose,
injected insulin has time characteristics inherent to the preparation
The picture to the right shows how a combination of fast and
slow insulins may become effective in time. The early spike is
due to the fast insulin. Click on the picture to select, on the
page that will open next, a specific combination of insulins
you want to know about.
to explain the way the software works: the curves represented
by the graphs demonstrate how nutrients convert to glucose
in the blood over time, after eating a complex meal. The mathematical
equations are those that describe the process of constant rate
diffusion through multiple interconnected compartments. Simple
sugars, carbohydrates, proteins and fats ingested will all
be converted sooner or later: evidently, simple sugars will
convert with a very fast diffusion rate and through fewer compartments,
while fats will take much, much longer, because of very slow
diffusion rates and more compartments.
many chambers, and what is the diffusion rate we use to model
the various types of nutrient? At this early state in our state
of knowledge about this important issue, the actual values
are probably far from definitive. The actual diffusion
rates we use in our formulas were calculated from published
clinical data, from
glycemic index data, when available, and from our own pre-clinical
trials at Duke Universitys Clinical Research Center (type 1